Amsterdam
Criteria
- At
least three relatives with histologically verified CRC;
- one
of the relatives should be a first degree relative to the
other two.
- Familial
adenomatous polyposis should be excluded.
- At
least two successive generations should be affected.
- In
one of the relatives CRC should be diagnosed under 50 years of
age.
International
Collaborative Group on HNPCC
(1990)
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